Studies, Clinical Trials, and Research Opportunities

By March 18, 2021July 8th, 2021Partner Highlights, Research

This is a running list of recruiting studies, clinical trials, and research opportunities. If you have an opportunity to add to this list, please contact us.

Federally-Funded Clinical Studies

ClinicalTrials.gov is a registry of clinical trials run by the United States National Library of Medicine (NLM) at the National Institutes of Health (NIH). This list is updated as more studies are announced.

You + ME Long COVID Study

The You + ME Registry is an online clinical study of individuals committed to identifying a cure for long-COVID and other post-viral illnesses.

Open to participants age 18+ who live in the United States or Australia.

Early Treatment of Long COVID with Ampligen (rintatolimod)

Many individuals who contract COVID develop persistent symptoms that resemble those of Chronic Fatigue Syndrome (or ME/CFS). Ampligen is an investigational drug that is being studied for the treatment of ME/CFS, and a recent publication (PLoS ONE 15(10): e0240403) concluded that early treatment of ME/CFS is most beneficial. This is a 6 month open label study to treat up to 20 Long Haulers with Ampligen to determine the safety and activity of the drug. Subjects must be between 16 and 65 years old, have a documented history of COVID-19, and meet accepted criteria for the diagnosis of ME/CFS.

Long COVID Patient Survey

Researchers at Stanford University and Stony Brook University partnered with patients to develop an online survey to gather information on patient experiences with acute and long term COVID-19 symptoms, and other information that may help researchers identify effective treatment strategies. The survey takes about 20 minutes to complete and provides the option to participate in follow-up studies.

Open to anyone who had confirmed or suspected COVID-19, age 18+

Johns Hopkins COVID Long Study

Research scientists from the Johns Hopkins Bloomberg School of Public Health want to learn more about people’s experience with COVID-19. To do this, we need to understand your experiences during and after your COVID-19 infection. The study consists of a short, online survey.

If you have tested positive for COVID-19 or experienced COVID-19 symptoms, we want to hear from you.

COVID-19 Patient Experience Survey #2

Following up with our previous survey, we are launching our new study, which will be examining antibody testing results, wider and more detailed symptoms, including neurological, cardiovascular, systemic and beyond, as well as the impact on mental health.

Open to those currently experiencing symptoms consistent with COVID-19 as a result of suspected or confirmed SARS-CoV-2 infection.

COVID-19 Longhauler Study

Clinical trial of a rehabilitation program for COVID long-haulers. After an initial consultation via Zoom, eligible participants will come to the Pulmonary Wellness Foundation’s COVID-19 Rehabilitation and Recovery Clinic at H&D Physical Therapy in New York City for an orthostatic tolerance test, pre- and post-treatment exercise tolerance tests and 24 treatment sessions that will involve aerobic exercise, supplemental oxygen, or both. They will also undergo an initial screening consultation and cognitive testing via Zoom, and complete daily and weekly questionnaires online.

Understanding COVID Recovery

This study aims to find whether the incidence of long COVID is higher in People with HIV and whether prolonged symptoms can be predicted with biomarkers in the blood at 1 month post-infection.

This is a national remote study open to anyone living in the contiguous lower 48 states of the USA and
• Enrolls people with (and without) HIV and a recent (within past 4 weeks) diagnosis of SARS-CoV-2 infection confirmed by RT-PCR testing.
• Administers surveys about symptoms and sequelae of COVID-19 over the course of a year over the phone or internet.
• Employs a mobile phlebotomy company to draw blood in the patient’s home at their convenience 2 times over the course of the study.
• Offers $50 in gift cards over the course of the study.
• Is offered in English or Spanish.

COVID-19 and Cognition Telephone Study

Researchers are studying cognition in Veterans and non-Veterans who have recovered from mild to moderate COVID-19, or who are experiencing long-term effects after mild to moderate COVID-19. This is a brief telephone study occurring across the U.S.